Medicinal preparation



Patented Aug. 8, 1939 MEDICINAL PREPARATION Oscar A. Strauss, Milwaukee,Wis.

No Drawing. Application April 22. 1937. I

Serial N0. 138,369

This invention relates-to improvements in medical compounds. Thisapplication is a continuation in part of my application Serial No.123,489 filed February 1, 1937.

It is the primary object of the present invention to provide a medicinalpreparation which may be injected intravenously or intramuscularly intohuman patients for the correction of dis- .turbances of the circulatorysystem. 10

sodium cacodylate in solution in distilled water or in a normal saltsolution. The strength of the iodine ingredient is notcritical andneither is the strength of the sodium cacodylate ingredient critmostsatisfactory, however, are as follows.

I prefer to employ a 10 c. 0. injection made up freshly of 9 c. c. of0.2% solution of colloidal iodine'in distilled water or normal saltsolution 30 It is important that the iodine be in true colloidal form.It is also important that the sodiumcacodylate be unoxidized. In usingingredients procured from certain domestic sources I have had occasionalunfavorable reactions in the patient, but where the ingredients areentirely pure and fresh and in accordance with the aforesaid standards,I have had no unfavorable reactions whatever and have had uniformlyexcellent results inthe treatment of angina pectoris, coro-' o narydiseases, and other latory system.

I am aware that sodium cacodylate, and even preparations of iodine, havebeen. used separatedisorders of the circuly for treatment of the sametypes of disorders, 45 but over along period it has been my experiencethat such treatments are merely palliatives and do not correct thecondition.

To accelerate the treatment, and also to assure permanence of result, Iprefer to add to the injection as above specified a minute quantity of 5hydrastinine, which may be added either .in crystalline form or in theform of an extract, fluid extract, tincture, or infusion. Hydrastinineis the active element in hydrast'is, hydrastin and hy The preparationconsists of colloidal iodine'and ical. The proportions which have beenfound 'stantial eifect.

drastina, any'of which may be substituted to give I a like amount of thehydrastinine ingredient.

The dosage used is' preferably on the order of $4 of a grain of thecrystalline hydrastinine hydrochloride, dissolved in the solutionaforesaid. In my experience it seems undesirable to use more than grainat the maximum, and I have not found less than of a grain to be of anysub-- These amounts are. given only by way of example and not with theidea of limit-' ing the appended claims. 2

I claim:

1. A preparation for the treatment of disturbances of the circulatorysystem, comprising a mixture of colloidal iodine with sodium cacodylate.v

2. A preparation for the treatment of disturbances of the circulatorysystem,-comprising colloidal iodine and sodium cacodylate in aqueoussolution for injection.

. 3. A preparation for the treatment of disturbances of thecirculato'rysystem which comprises approximately nine parts of colloidal iodine in a0.2% solution and approximately one part of an aqueous solutioncontaining approximately seven grains of sodium cacodylate. i 3

4. A preparation for the. treatment of disturbances of the circulatorysystem which comprises approximately nine parts of cglloidal iodine in a0.2% solutionand approximately one part of an aqueous solutioncontaining approximately seven 40 grains of sodium cacodylate, theingredients of said solutions being pure and the sodium cacodylate beingunoxidized, and the said solution being 1 freshly commlngled at the timeof injection.

' OSCAR A. STRAUSS.

